Has world-class expertise in the science of DNA and RNA, and develops multiplex PCR primer design softwareDNA Software The company's software on the company's website PanelPlex-Consensus The page about the response to the new coronavirus (COVID-19) has been released.
The following is information from the manufacturer.
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PanelPlex-Consensus Is a software for designing consensus PCR assays with high sensitivity and specificity for both viral and bacterial pathogens.
New Coronavirus (COVID-19) With the spread of the disease, scientists are looking for ways to quickly diagnose the virus with rapid testing techniques. Building a working assay is essential for speeding up the diagnostic process and controlling viral spread.
Why PanelPlex-Consensus can help you build a sensitive and specific PCR assay to detect SARS-CoV-2 (a new type of coronavirus), including all variants
・ PanelPlex-Consensus has been rigorously validated for the detection of thousands of bacteria, viruses and human targets.
・ PanelPlex-Consensus provides consensus designs PCR assays to detect all sequence variants of a given virus.Often, this is accomplished with a single primer pair (ie singleplex reaction) while in other cases with high sequence diversity a small multiplex reaction is required (typically 1 to 5 plex is required) .For example, we have made singleplex assays for pandemic 2009 H1N1 FluA, and 7-plex assay for the highly divergent Lassa virus.
・ PanelPlex-Consensus is fully capable of designing a new assay to address the (COVID-19) Coronavirus.PanelPlex-Consensus allows the user to input panels of GenBank accessions to form inclusivity, exclusivity (ie phylogenetically near neighbor sequences), and background databases .
・ PanelPlex-Consensus uses our proprietary ThermoBLAST and TargAn (target analysis), algorithms so that the assays are designed with maximum coverage of sequence variants with minimum false positives and false
・ PanelPlex-Consensus saves over six months on average of iterative experimental trial-and-error optimization.
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